LIMS1 FISH Probe
The LIMS1 FISH probe is designed to hybridize to the LIMS1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| LIMS1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| LIMS1-20-RE | 20 (40 μL) | 200 μL |  |
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| LIMS1-20-GO | 20 (40 μL) | 200 μL |  |
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| LIMS1-20-GR | 20 (40 μL) | 200 μL |  |
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| LIMS1-20-AQ | 20 (40 μL) | 200 μL |  |
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| LIMS1-20-DIG | 20 (40 μL) | 200 μL |  |
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| LIMS1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is an adaptor protein which contains five LIM domains, or double zinc fingers. The protein is likely involved in integrin signaling through its LIM domain-mediated interaction with integrin-linked kinase, found in focal adhesion plaques. It is also thought to act as a bridge linking integrin-linked kinase to NCK adaptor protein 2, which is involved in growth factor receptor kinase signaling pathways. Its localization to the periphery of spreading cells also suggests that this protein may play a role in integrin-mediated cell adhesion or spreading. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2010]
Gene Details
Gene Symbol: LIMS1
Gene Name: LIM Zinc Finger Domain Containing 1
Chromosome: CHR2: 109150810-109303702
Locus: 2q12.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: LIMS1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: LIMS1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping