LILRB2 Break Apart FISH Probe
Empire Genomics’ LILRB2 Break Apart FISH Probe is designed to flank the LILRB2 gene and is typically used for detecting LILRB2 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in green and orange by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| LILRB2BA-20-GROR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| LILRB2BA-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| LILRB2BA-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| LILRB2BA-20-GORE | 20 (40 μL) | 200 μL |
|
|
| LILRB2BA-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| LILRB2BA-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| LILRB2BA-20-ORGR | 20 (40 μL) | 200 μL |
|
|
| LILRB2BA-20-REGO | 20 (40 μL) | 200 μL |
|
|
| LILRB2BA-20-REGR | 20 (40 μL) | 200 μL |
|
Gene Summary
This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: LILRB2
Gene Name: Leukocyte Immunoglobulin Like Receptor B2
Chromosome: CHR19: 54777674-54785033
Locus: 19q13.42
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|
Customer Publications
Product Details
Product: LILRB2 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: LILRB2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping