LIFR Break Apart FISH Probe
Empire Genomics’ LIFR Break Apart FISH Probe is designed to flank the LIFR gene and is typically used for detecting LIFR rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in green and orange by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| LIFRBA-20-GROR (Standard Design) | 20 (40 μL) | 200 μL |
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| LIFRBA-20-AQOR | 20 (40 μL) | 200 μL |
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| LIFRBA-20-GOGR | 20 (40 μL) | 200 μL |
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| LIFRBA-20-GORE | 20 (40 μL) | 200 μL |
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| LIFRBA-20-GRGO | 20 (40 μL) | 200 μL |
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| LIFRBA-20-GRRE | 20 (40 μL) | 200 μL |
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| LIFRBA-20-ORGR | 20 (40 μL) | 200 μL |
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| LIFRBA-20-REGO | 20 (40 μL) | 200 μL |
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| LIFRBA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
This gene encodes a protein that belongs to the type I cytokine receptor family. This protein combines with a high-affinity converter subunit, gp130, to form a receptor complex that mediates the action of the leukemia inhibitory factor, a polyfunctional cytokine that is involved in cellular differentiation, proliferation and survival in the adult and the embryo. Mutations in this gene cause Schwartz-Jampel syndrome type 2, a disease belonging to the group of the bent-bone dysplasias. A translocation that involves the promoter of this gene, t(5;8)(p13;q12) with the pleiomorphic adenoma gene 1, is associated with salivary gland pleiomorphic adenoma, a common type of benign epithelial tumor of the salivary gland. Multiple splice variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: LIFR
Gene Name: LIF Receptor Alpha
Chromosome: CHR5: 38475064-38595507
Locus: 5p13.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: LIFR FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: LIFR-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping