LH FISH Probe
The LH FISH probe is designed to hybridize to the LH gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PLOD1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| PLOD1-20-RE | 20 (40 μL) | 200 μL |  |
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| PLOD1-20-GO | 20 (40 μL) | 200 μL |  |
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| PLOD1-20-GR | 20 (40 μL) | 200 μL |  |
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| PLOD1-20-AQ | 20 (40 μL) | 200 μL |  |
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| PLOD1-20-DIG | 20 (40 μL) | 200 μL |  |
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| PLOD1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
Lysyl hydroxylase is a membrane-bound homodimeric protein localized to the cisternae of the endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VI have deficiencies in lysyl hydroxylase activity. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2015]
Gene Details
Gene Symbol: PLOD1
Gene Name: Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1
Chromosome: CHR1: 11994723-12035599
Locus: 1p36.22
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: LH FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: PLOD1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping