LGMN1 FISH Probe
The LGMN1 FISH probe is designed to hybridize to the LGMN1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| LGMN-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| LGMN-20-RE | 20 (40 μL) | 200 μL |  |
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| LGMN-20-GO | 20 (40 μL) | 200 μL |  |
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| LGMN-20-GR | 20 (40 μL) | 200 μL |  |
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| LGMN-20-AQ | 20 (40 μL) | 200 μL |  |
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| LGMN-20-DIG | 20 (40 μL) | 200 μL |  |
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| LGMN-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a cysteine protease that has a strict specificity for hydrolysis of asparaginyl bonds. This enzyme may be involved in the processing of bacterial peptides and endogenous proteins for MHC class II presentation in the lysosomal/endosomal systems. Enzyme activation is triggered by acidic pH and appears to be autocatalytic. Protein expression occurs after monocytes differentiate into dendritic cells. A fully mature, active enzyme is produced following lipopolysaccharide expression in mature dendritic cells. Overexpression of this gene may be associated with the majority of solid tumor types. This gene has a pseudogene on chromosome 13. Several alternatively spliced transcript variants have been described, but the biological validity of only two has been determined. These two variants encode the same isoform. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: LGMN
Gene Name: Legumain
Chromosome: CHR14: 93170151-93215047
Locus: 14q32.12
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: LGMN1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: LGMN-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping