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LGMN FISH Probe

The LGMN FISH probe is designed to hybridize to the LGMN gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

SKU Test Kits Buffer Dye Color Order Now
LGMN-20-OR  (Standard Design) 20 (40 μL) 200 μL
LGMN-20-RE 20 (40 μL) 200 μL
LGMN-20-GO 20 (40 μL) 200 μL
LGMN-20-GR 20 (40 μL) 200 μL
LGMN-20-AQ 20 (40 μL) 200 μL
LGMN-20-DIG 20 (40 μL) 200 μL
LGMN-20-BIO 20 (40 μL) 200 μL

Gene Summary

This gene encodes a cysteine protease that has a strict specificity for hydrolysis of asparaginyl bonds. This enzyme may be involved in the processing of bacterial peptides and endogenous proteins for MHC class II presentation in the lysosomal/endosomal systems. Enzyme activation is triggered by acidic pH and appears to be autocatalytic. Protein expression occurs after monocytes differentiate into dendritic cells. A fully mature, active enzyme is produced following lipopolysaccharide expression in mature dendritic cells. Overexpression of this gene may be associated with the majority of solid tumor types. This gene has a pseudogene on chromosome 13. Several alternatively spliced transcript variants have been described, but the biological validity of only two has been determined. These two variants encode the same isoform. [provided by RefSeq, Jul 2008]

Gene Details

Gene Symbol: LGMN

Gene Name: Legumain

Chromosome: CHR14: 93170151-93215047

Locus: 14q32.12

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Scientific Citations

There are currently no FISH related citations for this gene.

Product Details

Product: LGMN FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: LGMN-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping