LGMD1C FISH Probe
The LGMD1C FISH probe is designed to hybridize to the LGMD1C gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CAV3-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
|
| CAV3-20-RE | 20 (40 μL) | 200 μL |  |
|
| CAV3-20-GO | 20 (40 μL) | 200 μL |  |
|
| CAV3-20-GR | 20 (40 μL) | 200 μL |  |
|
| CAV3-20-AQ | 20 (40 μL) | 200 μL |  |
|
| CAV3-20-DIG | 20 (40 μL) | 200 μL |  |
|
| CAV3-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a caveolin family member, which functions as a component of the caveolae plasma membranes found in most cell types. Caveolin proteins are proposed to be scaffolding proteins for organizing and concentrating certain caveolin-interacting molecules. Mutations identified in this gene lead to interference with protein oligomerization or intra-cellular routing, disrupting caveolae formation and resulting in Limb-Girdle muscular dystrophy type-1C (LGMD-1C), hyperCKemia or rippling muscle disease (RMD). Alternative splicing has been identified for this locus, with inclusion or exclusion of a differentially spliced intron. In addition, transcripts utilize multiple polyA sites and contain two potential translation initiation sites. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: CAV3
Gene Name: Caveolin 3
Chromosome: CHR3: 8775485-8788451
Locus: 3p25.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|
Customer Publications
Product Details
Product: LGMD1C FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: CAV3-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping