LFNG Break Apart FISH Probe
Empire Genomics’ LFNG Break Apart FISH Probe is designed to flank the LFNG gene and is typically used for detecting LFNG rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| LFNGBA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| LFNGBA-20-AQOR | 20 (40 μL) | 200 μL |
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| LFNGBA-20-GOGR | 20 (40 μL) | 200 μL |
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| LFNGBA-20-GORE | 20 (40 μL) | 200 μL |
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| LFNGBA-20-GRGO | 20 (40 μL) | 200 μL |
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| LFNGBA-20-GROR | 20 (40 μL) | 200 μL |
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| LFNGBA-20-GRRE | 20 (40 μL) | 200 μL |
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| LFNGBA-20-REGO | 20 (40 μL) | 200 μL |
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| LFNGBA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
This gene is a member of the fringe gene family which also includes radical and manic fringe genes. They all encode evolutionarily conserved glycosyltransferases that act in the Notch signaling pathway to define boundaries during embryonic development. While their genomic structure is distinct from other glycosyltransferases, fringe proteins have a fucose-specific beta-1,3-N-acetylglucosaminyltransferase activity that leads to elongation of O-linked fucose residues on Notch, which alters Notch signaling. This gene product is predicted to be a single-pass type II Golgi membrane protein but it may also be secreted and proteolytically processed like the related proteins in mouse and Drosophila (PMID: 9187150). Mutations in this gene have been associated with autosomal recessive spondylocostal dysostosis 3. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]
Gene Details
Gene Symbol: LFNG
Gene Name: LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
Chromosome: CHR7: 2552162-2568063
Locus: 7p22.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: LFNG FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: LFNG-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping