LFNG FISH Probe
The LFNG FISH probe is designed to hybridize to the LFNG gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| LFNG-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| LFNG-20-RE | 20 (40 μL) | 200 μL |  |
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| LFNG-20-GO | 20 (40 μL) | 200 μL |  |
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| LFNG-20-GR | 20 (40 μL) | 200 μL |  |
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| LFNG-20-AQ | 20 (40 μL) | 200 μL |  |
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| LFNG-20-DIG | 20 (40 μL) | 200 μL |  |
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| LFNG-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene is a member of the fringe gene family which also includes radical and manic fringe genes. They all encode evolutionarily conserved glycosyltransferases that act in the Notch signaling pathway to define boundaries during embryonic development. While their genomic structure is distinct from other glycosyltransferases, fringe proteins have a fucose-specific beta-1,3-N-acetylglucosaminyltransferase activity that leads to elongation of O-linked fucose residues on Notch, which alters Notch signaling. This gene product is predicted to be a single-pass type II Golgi membrane protein but it may also be secreted and proteolytically processed like the related proteins in mouse and Drosophila (PMID: 9187150). Mutations in this gene have been associated with autosomal recessive spondylocostal dysostosis 3. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]
Gene Details
Gene Symbol: LFNG
Gene Name: LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
Chromosome: CHR7: 2552162-2568063
Locus: 7p22.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: LFNG FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: LFNG-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping