LEPR FISH Probe
The LEPR FISH probe is designed to hybridize to the LEPR gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| LEPR-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| LEPR-20-RE | 20 (40 μL) | 200 μL |  |
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| LEPR-20-GO | 20 (40 μL) | 200 μL |  |
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| LEPR-20-GR | 20 (40 μL) | 200 μL |  |
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| LEPR-20-AQ | 20 (40 μL) | 200 μL |  |
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| LEPR-20-DIG | 20 (40 μL) | 200 μL |  |
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| LEPR-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene belongs to the gp130 family of cytokine receptors that are known to stimulate gene transcription via activation of cytosolic STAT proteins. This protein is a receptor for leptin (an adipocyte-specific hormone that regulates body weight), and is involved in the regulation of fat metabolism, as well as in a novel hematopoietic pathway that is required for normal lymphopoiesis. Mutations in this gene have been associated with obesity and pituitary dysfunction. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. It is noteworthy that this gene and LEPROT gene (GeneID:54741) share the same promoter and the first 2 exons, however, encode distinct proteins (PMID:9207021).[provided by RefSeq, Nov 2010]
Gene Details
Gene Symbol: LEPR
Gene Name: Leptin Receptor
Chromosome: CHR1: 65886334-66103176
Locus: 1p31.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: LEPR FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: LEPR-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping