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LEP Break Apart FISH Probe

Empire Genomics’ LEP Break Apart FISH Probe is designed to flank the LEP gene and is typically used for detecting LEP rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
LEPBA-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
LEPBA-20-AQOR 20 (40 μL) 200 μL
LEPBA-20-GOGR 20 (40 μL) 200 μL
LEPBA-20-GORE 20 (40 μL) 200 μL
LEPBA-20-GRGO 20 (40 μL) 200 μL
LEPBA-20-GROR 20 (40 μL) 200 μL
LEPBA-20-GRRE 20 (40 μL) 200 μL
LEPBA-20-REGO 20 (40 μL) 200 μL
LEPBA-20-REGR 20 (40 μL) 200 μL

Gene Summary

This gene encodes a protein that is secreted by white adipocytes into the circulation and plays a major role in the regulation of energy homeostasis. Circulating leptin binds to the leptin receptor in the brain, which activates downstream signaling pathways that inhibit feeding and promote energy expenditure. This protein also has several endocrine functions, and is involved in the regulation of immune and inflammatory responses, hematopoiesis, angiogenesis, reproduction, bone formation and wound healing. Mutations in this gene and its regulatory regions cause severe obesity and morbid obesity with hypogonadism in human patients. A mutation in this gene has also been linked to type 2 diabetes mellitus development. [provided by RefSeq, Aug 2017]

Gene Details

Gene Symbol: LEP

Gene Name: Leptin

Chromosome: CHR7: 127881330-127897682

Locus: 7q32.1

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: LEP FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: LEP-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping