LEKTI FISH Probe
The LEKTI FISH probe is designed to hybridize to the LEKTI gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SPINK5-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| SPINK5-20-RE | 20 (40 μL) | 200 μL |  |
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| SPINK5-20-GO | 20 (40 μL) | 200 μL |  |
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| SPINK5-20-GR | 20 (40 μL) | 200 μL |  |
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| SPINK5-20-AQ | 20 (40 μL) | 200 μL |  |
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| SPINK5-20-DIG | 20 (40 μL) | 200 μL |  |
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| SPINK5-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a multidomain serine protease inhibitor that contains 15 potential inhibitory domains. The encoded preproprotein is proteolytically processed to generate multiple protein products, which may exhibit unique activities and specificities. These proteins may play a role in skin and hair morphogenesis, as well as anti-inflammatory and antimicrobial protection of mucous epithelia. Mutations in this gene may result in Netherton syndrome, a disorder characterized by ichthyosis, defective cornification, and atopy. This gene is present in a gene cluster on chromosome 5. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015]
Gene Details
Gene Symbol: SPINK5
Gene Name: Serine Peptidase Inhibitor, Kazal Type 5
Chromosome: CHR5: 147443534-147516925
Locus: 5q32
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: LEKTI FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: SPINK5-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping