LEF1 Break Apart FISH Probe
Empire Genomics’ LEF1 Break Apart FISH Probe is designed to flank the LEF1 gene and is typically used for detecting LEF1 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in green and orange by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| LEF1BA-20-GROR (Standard Design) | 20 (40 μL) | 200 μL |
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| LEF1BA-20-AQOR | 20 (40 μL) | 200 μL |
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| LEF1BA-20-GOGR | 20 (40 μL) | 200 μL |
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| LEF1BA-20-GORE | 20 (40 μL) | 200 μL |
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| LEF1BA-20-GRGO | 20 (40 μL) | 200 μL |
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| LEF1BA-20-GRRE | 20 (40 μL) | 200 μL |
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| LEF1BA-20-ORGR | 20 (40 μL) | 200 μL |
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| LEF1BA-20-REGO | 20 (40 μL) | 200 μL |
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| LEF1BA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
This gene encodes a member of the T-cell factor/lymphoid enhancer-binding factor family of high mobility group (HMG) box transcriptional activators. This gene is expressed predominantly in T-cells and plays a critical role in natural killer cell and innate lymphoid cell development. The encoded protein forms a complex with beta-catenin and activates transcription through a Wnt/beta-catenin signaling pathway. Mice with a knockout of this gene are viable and fertile, but display a block in T-lymphocyte differentiation. Alternative splicing results in multiple transcript variants. Naturally-occurring isoforms lacking the N-terminal beta-catenin interaction domain may act as dominant negative regulators of Wnt signaling. [provided by RefSeq, Oct 2016]
Gene Details
Gene Symbol: TCF7
Gene Name: Transcription Factor 7
Chromosome: CHR5: 133450401-133483920
Locus: 5q31.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: LEF1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: TCF7-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping