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LDLCQ2 FISH Probe

The LDLCQ2 FISH probe is designed to hybridize to the LDLCQ2 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
LDLR-20-OR  (Standard Design) 20 (40 μL) 200 μL
LDLR-20-RE 20 (40 μL) 200 μL
LDLR-20-GO 20 (40 μL) 200 μL
LDLR-20-GR 20 (40 μL) 200 μL
LDLR-20-AQ 20 (40 μL) 200 μL
LDLR-20-DIG 20 (40 μL) 200 μL
LDLR-20-BIO 20 (40 μL) 200 μL

Gene Summary

The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. Low density lipoprotein (LDL) is normally bound at the cell membrane and taken into the cell ending up in lysosomes where the protein is degraded and the cholesterol is made available for repression of microsomal enzyme 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting step in cholesterol synthesis. At the same time, a reciprocal stimulation of cholesterol ester synthesis takes place. Mutations in this gene cause the autosomal dominant disorder, familial hypercholesterolemia. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Sep 2010]

Gene Details

Gene Symbol: LDLR

Gene Name: Low Density Lipoprotein Receptor

Chromosome: CHR19: 11200037-11244505

Locus: 19p13.2

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: LDLCQ2 FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: LDLR-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping