LCK Break Apart FISH Probe
Empire Genomics’ LCK Break Apart FISH Probe is designed to flank the LCK gene and is typically used for detecting LCK rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
SKU | Test Kits | Buffer | Dye Color | Order Now |
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LCKBA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL | ||
LCKBA-20-AQOR | 20 (40 μL) | 200 μL | ||
LCKBA-20-GOGR | 20 (40 μL) | 200 μL | ||
LCKBA-20-GORE | 20 (40 μL) | 200 μL | ||
LCKBA-20-GRGO | 20 (40 μL) | 200 μL | ||
LCKBA-20-GROR | 20 (40 μL) | 200 μL | ||
LCKBA-20-GRRE | 20 (40 μL) | 200 μL | ||
LCKBA-20-REGO | 20 (40 μL) | 200 μL | ||
LCKBA-20-REGR | 20 (40 μL) | 200 μL |
Gene Summary
This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein is a key signaling molecule in the selection and maturation of developing T-cells. It contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to the plasma membrane and pericentrosomal vesicles, and binds to cell surface receptors, including CD4 and CD8, and other signaling molecules. Multiple alternatively spliced variants encoding different isoforms have been described. [provided by RefSeq, Aug 2016]
Gene Details
Gene Symbol: LCK
Gene Name: LCK Proto-oncogene, Src Family Tyrosine Kinase
Chromosome: CHR1: 32716839-32751766
Locus: 1p35.2
FISH Probe Protocols
Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: LCK FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: LCK-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping