LAP1 FISH Probe
The LAP1 FISH probe is designed to hybridize to the LAP1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| TRAF3-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| TRAF3-20-RE | 20 (40 μL) | 200 μL |  |
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| TRAF3-20-GO | 20 (40 μL) | 200 μL |  |
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| TRAF3-20-GR | 20 (40 μL) | 200 μL |  |
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| TRAF3-20-AQ | 20 (40 μL) | 200 μL |  |
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| TRAF3-20-DIG | 20 (40 μL) | 200 μL |  |
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| TRAF3-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from, members of the TNF receptor (TNFR) superfamily. This protein participates in the signal transduction of CD40, a TNFR family member important for the activation of the immune response. This protein is found to be a critical component of the lymphotoxin-beta receptor (LTbetaR) signaling complex, which induces NF-kappaB activation and cell death initiated by LTbeta ligation. Epstein-Barr virus encoded latent infection membrane protein-1 (LMP1) can interact with this and several other members of the TRAF family, which may be essential for the oncogenic effects of LMP1. Several alternatively spliced transcript variants encoding three distinct isoforms have been reported. [provided by RefSeq, Dec 2010]
Gene Details
Gene Symbol: TRAF3
Gene Name: TNF Receptor Associated Factor 3
Chromosome: CHR14: 103243815-103377837
Locus: 14q32.32
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: LAP1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: TRAF3-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping