LAM FISH Probe
The LAM FISH probe is designed to hybridize to the LAM gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| LMNA-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| LMNA-20-RE | 20 (40 μL) | 200 μL |  |
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| LMNA-20-GO | 20 (40 μL) | 200 μL |  |
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| LMNA-20-GR | 20 (40 μL) | 200 μL |  |
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| LMNA-20-AQ | 20 (40 μL) | 200 μL |  |
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| LMNA-20-DIG | 20 (40 μL) | 200 μL |  |
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| LMNA-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Alternative splicing results in multiple transcript variants. Mutations in this gene lead to several diseases: Emery-Dreifuss muscular dystrophy, familial partial lipodystrophy, limb girdle muscular dystrophy, dilated cardiomyopathy, Charcot-Marie-Tooth disease, and Hutchinson-Gilford progeria syndrome. [provided by RefSeq, Apr 2012]
Gene Details
Gene Symbol: LMNA
Gene Name: Lamin A/C
Chromosome: CHR1: 156084460-156109878
Locus: 1q22
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: LAM FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: LMNA-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping