L1CAM FISH Probe
The L1CAM FISH probe is designed to hybridize to the L1CAM gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| L1CAM-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| L1CAM-20-RE | 20 (40 μL) | 200 μL |  |
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| L1CAM-20-GO | 20 (40 μL) | 200 μL |  |
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| L1CAM-20-GR | 20 (40 μL) | 200 μL |  |
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| L1CAM-20-AQ | 20 (40 μL) | 200 μL |  |
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| L1CAM-20-DIG | 20 (40 μL) | 200 μL |  |
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| L1CAM-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause X-linked neurological syndromes known as CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus). Alternative splicing of this gene results in multiple transcript variants, some of which include an alternate exon that is considered to be specific to neurons. [provided by RefSeq, May 2013]
Gene Details
Gene Symbol: L1CAM
Gene Name: L1 Cell Adhesion Molecule
Chromosome: CHRX: 153126970-153141399
Locus: Xq28
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: L1CAM FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: L1CAM-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping