L FISH Probe
The L FISH probe is designed to hybridize to the L gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CCNT1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| CCNT1-20-RE | 20 (40 μL) | 200 μL |  |
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| CCNT1-20-GO | 20 (40 μL) | 200 μL |  |
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| CCNT1-20-GR | 20 (40 μL) | 200 μL |  |
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| CCNT1-20-AQ | 20 (40 μL) | 200 μL |  |
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| CCNT1-20-DIG | 20 (40 μL) | 200 μL |  |
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| CCNT1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a member of the highly conserved cyclin C subfamily. The encoded protein tightly associates with cyclin-dependent kinase 9, and is a major subunit of positive transcription elongation factor b (p-TEFb). In humans, there are multiple forms of positive transcription elongation factor b, which may include one of several different cyclins along with cyclin-dependent kinase 9. The complex containing the encoded cyclin and cyclin-dependent kinase 9 acts as a cofactor of human immunodeficiency virus type 1 (HIV-1) Tat protein, and is both necessary and sufficient for full activation of viral transcription. This cyclin and its kinase partner are also involved in triggering transcript elongation through phosphorylation of the carboxy-terminal domain of the largest RNA polymerase II subunit. Overexpression of this gene is implicated in tumor growth. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2013]
Gene Details
Gene Symbol: CCNT1
Gene Name: Cyclin T1
Chromosome: CHR12: 49086751-49110781
Locus: 12q13.11-q13.12
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: L FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: CCNT1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping