KRIT1 FISH Probe
The KRIT1 FISH probe is designed to hybridize to the KRIT1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| KRIT1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| KRIT1-20-RE | 20 (40 μL) | 200 μL |  |
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| KRIT1-20-GO | 20 (40 μL) | 200 μL |  |
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| KRIT1-20-GR | 20 (40 μL) | 200 μL |  |
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| KRIT1-20-AQ | 20 (40 μL) | 200 μL |  |
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| KRIT1-20-DIG | 20 (40 μL) | 200 μL |  |
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| KRIT1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a protein containing four ankyrin repeats, a band 4.1/ezrin/radixin/moesin (FERM) domain, and multiple NPXY sequences. The encoded protein is localized in the nucleus and cytoplasm. It binds to integrin cytoplasmic domain-associated protein-1 alpha (ICAP1alpha), and plays a critical role in beta1-integrin-mediated cell proliferation. It associates with junction proteins and RAS-related protein 1A (Rap1A), which requires the encoded protein for maintaining the integrity of endothelial junctions. It is also a microtubule-associated protein and may play a role in microtubule targeting. Mutations in this gene result in cerebral cavernous malformations. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2009]
Gene Details
Gene Symbol: KRIT1
Gene Name: KRIT1, Ankyrin Repeat Containing
Chromosome: CHR7: 91828282-91875414
Locus: 7q21.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: KRIT1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: KRIT1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping