KREMEN2 FISH Probe
The KREMEN2 FISH probe is designed to hybridize to the KREMEN2 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| KREMEN2-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| KREMEN2-20-RE | 20 (40 μL) | 200 μL |  |
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| KREMEN2-20-GO | 20 (40 μL) | 200 μL |  |
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| KREMEN2-20-GR | 20 (40 μL) | 200 μL |  |
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| KREMEN2-20-AQ | 20 (40 μL) | 200 μL |  |
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| KREMEN2-20-DIG | 20 (40 μL) | 200 μL |  |
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| KREMEN2-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor. A similar protein in mouse functions interacts with with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein forms a ternary membrane complex with DKK1 and the WNT receptor lipoprotein receptor-related protein 6 (LRP6), and induces rapid endocytosis and removal of LRP6 from the plasma membrane. It contains extracellular kringle, WSC, and CUB domains. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
Gene Details
Gene Symbol: KREMEN2
Gene Name: Kringle Containing Transmembrane Protein 2
Chromosome: CHR16: 3014216-3018381
Locus: 16p13.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: KREMEN2 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: KREMEN2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping