KNG1 Break Apart FISH Probe
Empire Genomics’ KNG1 Break Apart FISH Probe is designed to flank the KNG1 gene and is typically used for detecting KNG1 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
SKU | Test Kits | Buffer | Dye Color | Order Now |
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KNG1BA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL | ||
KNG1BA-20-AQOR | 20 (40 μL) | 200 μL | ||
KNG1BA-20-GOGR | 20 (40 μL) | 200 μL | ||
KNG1BA-20-GORE | 20 (40 μL) | 200 μL | ||
KNG1BA-20-GRGO | 20 (40 μL) | 200 μL | ||
KNG1BA-20-GROR | 20 (40 μL) | 200 μL | ||
KNG1BA-20-GRRE | 20 (40 μL) | 200 μL | ||
KNG1BA-20-REGO | 20 (40 μL) | 200 μL | ||
KNG1BA-20-REGR | 20 (40 μL) | 200 μL |
Gene Summary
This gene uses alternative splicing to generate two different proteins- high molecular weight kininogen (HMWK) and low molecular weight kininogen (LMWK). HMWK is essential for blood coagulation and assembly of the kallikrein-kinin system. Also, bradykinin, a peptide causing numerous physiological effects, is released from HMWK. Bradykinin also functions as an antimicrobial peptide with antibacterial and antifungal activity. In contrast to HMWK, LMWK is not involved in blood coagulation. Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Nov 2014]
Gene Details
Gene Symbol: KNG1
Gene Name: Kininogen 1
Chromosome: CHR3: 186435097-186462199
Locus: 3q27.3
FISH Probe Protocols
Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: KNG1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: KNG1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping