KN FISH Probe
The KN FISH probe is designed to hybridize to the KN gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| KANK1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| KANK1-20-RE | 20 (40 μL) | 200 μL |  |
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| KANK1-20-GO | 20 (40 μL) | 200 μL |  |
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| KANK1-20-GR | 20 (40 μL) | 200 μL |  |
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| KANK1-20-AQ | 20 (40 μL) | 200 μL |  |
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| KANK1-20-DIG | 20 (40 μL) | 200 μL |  |
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| KANK1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene belongs to the Kank family of proteins, which contain multiple ankyrin repeat domains. This family member functions in cytoskeleton formation by regulating actin polymerization. This gene is a candidate tumor suppressor for renal cell carcinoma. Mutations in this gene cause cerebral palsy spastic quadriplegic type 2, a central nervous system development disorder. A t(5;9) translocation results in fusion of the platelet-derived growth factor receptor beta gene (PDGFRB) on chromosome 5 with this gene in a myeloproliferative neoplasm featuring severe thrombocythemia. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome 20. [provided by RefSeq, Dec 2014]
Gene Details
Gene Symbol: KANK1
Gene Name: KN Motif And Ankyrin Repeat Domains 1
Chromosome: CHR9: 504702-746103
Locus: 9p24.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: KN FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: KANK1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping