KLKB1 FISH Probe
The KLKB1 FISH probe is designed to hybridize to the KLKB1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| F11-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| F11-20-RE | 20 (40 μL) | 200 μL |  |
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| F11-20-GO | 20 (40 μL) | 200 μL |  |
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| F11-20-GR | 20 (40 μL) | 200 μL |  |
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| F11-20-AQ | 20 (40 μL) | 200 μL |  |
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| F11-20-DIG | 20 (40 μL) | 200 μL |  |
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| F11-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes coagulation factor XI of the blood coagulation cascade. This protein is present in plasma as a zymogen, which is a unique plasma coagulation enzyme because it exists as a homodimer consisting of two identical polypeptide chains linked by disulfide bonds. During activation of the plasma factor XI, an internal peptide bond is cleaved by factor XIIa (or XII) in each of the two chains, resulting in activated factor XIa, a serine protease composed of two heavy and two light chains held together by disulfide bonds. This activated plasma factor XI triggers the middle phase of the intrisic pathway of blood coagulation by activating factor IX. Defects in this factor lead to Rosenthal syndrome, a blood coagulation abnormality. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: F11
Gene Name: Coagulation Factor XI
Chromosome: CHR4: 187187117-187210835
Locus: 4q35.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: KLKB1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: F11-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping