KLC 1 FISH Probe
The KLC 1 FISH probe is designed to hybridize to the KLC 1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| KLC1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| KLC1-20-RE | 20 (40 μL) | 200 μL |  |
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| KLC1-20-GO | 20 (40 μL) | 200 μL |  |
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| KLC1-20-GR | 20 (40 μL) | 200 μL |  |
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| KLC1-20-AQ | 20 (40 μL) | 200 μL |  |
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| KLC1-20-DIG | 20 (40 μL) | 200 μL |  |
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| KLC1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
Conventional kinesin is a tetrameric molecule composed of two heavy chains and two light chains, and transports various cargos along microtubules toward their plus ends. The heavy chains provide the motor activity, while the light chains bind to various cargos. This gene encodes a member of the kinesin light chain family. It associates with kinesin heavy chain through an N-terminal domain, and six tetratricopeptide repeat (TPR) motifs are thought to be involved in binding of cargos such as vesicles, mitochondria, and the Golgi complex. Thus, kinesin light chains function as adapter molecules and not motors per se. Although previously named "kinesin 2", this gene is not a member of the kinesin-2 / kinesin heavy chain subfamily of kinesin motor proteins. Extensive alternative splicing produces isoforms with different C-termini that are proposed to bind to different cargos; however, the full-length nature and/or biological validity of most of these variants have not been determined. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: KLC1
Gene Name: Kinesin Light Chain 1
Chromosome: CHR14: 104095524-104167888
Locus: 14q32.33
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: KLC 1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: KLC1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping