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KIR3DL1 FISH Probe

The KIR3DL1 FISH probe is designed to hybridize to the KIR3DL1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

SKU Test Kits Buffer Dye Color Order Now
KIR3DL1-20-OR  (Standard Design) 20 (40 μL) 200 μL
KIR3DL1-20-RE 20 (40 μL) 200 μL
KIR3DL1-20-GO 20 (40 μL) 200 μL
KIR3DL1-20-GR 20 (40 μL) 200 μL
KIR3DL1-20-AQ 20 (40 μL) 200 μL
KIR3DL1-20-DIG 20 (40 μL) 200 μL
KIR3DL1-20-BIO 20 (40 μL) 200 μL

Gene Summary

Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several "framework" genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules; thus, KIR proteins are thought to play an important role in regulation of the immune response. [provided by RefSeq, Jul 2008]

Gene Details

Gene Symbol: KIR3DL1

Gene Name: Killer Cell Immunoglobulin Like Receptor, Three Ig Domains And Long Cytoplasmic Tail 1

Chromosome: CHR19: 55327892-55342233

Locus: 19q13.42

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Scientific Citations

There are currently no FISH related citations for this gene.

Product Details

Product: KIR3DL1 FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: KIR3DL1-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping