KDM7B FISH Probe
The KDM7B FISH probe is designed to hybridize to the KDM7B gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PHF8-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| PHF8-20-RE | 20 (40 μL) | 200 μL |  |
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| PHF8-20-GO | 20 (40 μL) | 200 μL |  |
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| PHF8-20-GR | 20 (40 μL) | 200 μL |  |
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| PHF8-20-AQ | 20 (40 μL) | 200 μL |  |
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| PHF8-20-DIG | 20 (40 μL) | 200 μL |  |
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| PHF8-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is a histone lysine demethylase that preferentially acts on histones in the monomethyl or dimethyl states. The encoded protein requires Fe(2+) ion, 2-oxoglutarate, and oxygen for its catalytic activity. The protein has an N-terminal PHD finger and a central Jumonji C domain. This gene is thought to function as a transcription activator. Defects in this gene are a cause of syndromic X-linked Siderius type intellectual disability (MRXSSD) and over-expression of this gene is associated with several forms of cancer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2017]
Gene Details
Gene Symbol: PHF8
Gene Name: PHD Finger Protein 8
Chromosome: CHRX: 53963112-54071569
Locus: Xp11.22
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: KDM7B FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: PHF8-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping