KDM7A Break Apart FISH Probe
Empire Genomics’ KDM7A Break Apart FISH Probe is designed to flank the KDM7A gene and is typically used for detecting KDM7A rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in green and orange by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| KDM7ABA-20-GROR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| KDM7ABA-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| KDM7ABA-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| KDM7ABA-20-GORE | 20 (40 μL) | 200 μL |
|
|
| KDM7ABA-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| KDM7ABA-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| KDM7ABA-20-ORGR | 20 (40 μL) | 200 μL |
|
|
| KDM7ABA-20-REGO | 20 (40 μL) | 200 μL |
|
|
| KDM7ABA-20-REGR | 20 (40 μL) | 200 μL |
|
Gene Summary
The protein encoded by this gene is a histone lysine demethylase that preferentially acts on histones in the monomethyl or dimethyl states. The encoded protein requires Fe(2+) ion, 2-oxoglutarate, and oxygen for its catalytic activity. The protein has an N-terminal PHD finger and a central Jumonji C domain. This gene is thought to function as a transcription activator. Defects in this gene are a cause of syndromic X-linked Siderius type intellectual disability (MRXSSD) and over-expression of this gene is associated with several forms of cancer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2017]
Gene Details
Gene Symbol: PHF8
Gene Name: PHD Finger Protein 8
Chromosome: CHRX: 53963112-54071569
Locus: Xp11.22
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|
Customer Publications
Product Details
Product: KDM7A FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: PHF8-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping