KDM2A FISH Probe
The KDM2A FISH probe is designed to hybridize to the KDM2A gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
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| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| KDM2A-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| KDM2A-20-RE | 20 (40 μL) | 200 μL |  |
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| KDM2A-20-GO | 20 (40 μL) | 200 μL |  |
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| KDM2A-20-GR | 20 (40 μL) | 200 μL |  |
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| KDM2A-20-AQ | 20 (40 μL) | 200 μL |  |
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| KDM2A-20-DIG | 20 (40 μL) | 200 μL |  |
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| KDM2A-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains at least six highly degenerated leucine-rich repeats. This family member plays a role in epigenetic silencing. It nucleates at CpG islands and specifically demethylates both mono- and di-methylated lysine-36 of histone H3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2012]
Gene Details
Gene Symbol: KDM2A
Gene Name: Lysine Demethylase 2A
Chromosome: CHR11: 66886739-67025550
Locus: 11q13.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: KDM2A FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: KDM2A-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping