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KCS2 FISH Probe

The KCS2 FISH probe is designed to hybridize to the KCS2 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
FAM111A-20-OR  (Standard Design) 20 (40 μL) 200 μL
FAM111A-20-RE 20 (40 μL) 200 μL
FAM111A-20-GO 20 (40 μL) 200 μL
FAM111A-20-GR 20 (40 μL) 200 μL
FAM111A-20-AQ 20 (40 μL) 200 μL
FAM111A-20-DIG 20 (40 μL) 200 μL
FAM111A-20-BIO 20 (40 μL) 200 μL

Gene Summary

The protein encoded by this gene is cell-cycle regulated, and has nuclear localization. The C-terminal half of the protein shares homology with trypsin-like peptidases and it contains a PCNA-interacting peptide (PIP) box, that is necessary for its co-localization with proliferating cell nuclear antigen (PCNA). Reduced expression of this gene resulted in DNA replication defects, consistent with the demonstrated role for this gene in Simian Virus 40 (SV40) viral replication. Mutations in this gene have been associated with Kenny-Caffey syndrome (KCS) type 2 and the more severe osteocraniostenosis (OCS, also known as Gracile Bone Dysplasia), both characterized by short stature, hypoparathyroidism, bone development abnormalities, and hypocalcemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015]

Gene Details

Gene Symbol: FAM111A

Gene Name: Family With Sequence Similarity 111 Member A

Chromosome: CHR11: 58910317-58922511

Locus: 11q12.1

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: KCS2 FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: FAM111A-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping