KCNN3 FISH Probe
The KCNN3 FISH probe is designed to hybridize to the KCNN3 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| KCNN3-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| KCNN3-20-RE | 20 (40 μL) | 200 μL |  |
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| KCNN3-20-GO | 20 (40 μL) | 200 μL |  |
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| KCNN3-20-GR | 20 (40 μL) | 200 μL |  |
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| KCNN3-20-AQ | 20 (40 μL) | 200 μL |  |
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| KCNN3-20-DIG | 20 (40 μL) | 200 μL |  |
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| KCNN3-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. This gene belongs to the KCNN family of potassium channels. It encodes an integral membrane protein that forms a voltage-independent calcium-activated channel, which is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. This gene contains two CAG repeat regions in the coding sequence. It was thought that expansion of one or both of these repeats could lead to an increased susceptibility to schizophrenia or bipolar disorder, but studies indicate that this is probably not the case. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2011]
Gene Details
Gene Symbol: KCNN3
Gene Name: Potassium Calcium-activated Channel Subfamily N Member 3
Chromosome: CHR1: 154669941-154842754
Locus: 1q21.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: KCNN3 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: KCNN3-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping