KCNJ3 Break Apart FISH Probe
Empire Genomics’ KCNJ3 Break Apart FISH Probe is designed to flank the KCNJ3 gene and is typically used for detecting KCNJ3 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| KCNJ3BA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| KCNJ3BA-20-AQOR | 20 (40 μL) | 200 μL |
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| KCNJ3BA-20-GOGR | 20 (40 μL) | 200 μL |
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| KCNJ3BA-20-GORE | 20 (40 μL) | 200 μL |
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| KCNJ3BA-20-GRGO | 20 (40 μL) | 200 μL |
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| KCNJ3BA-20-GROR | 20 (40 μL) | 200 μL |
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| KCNJ3BA-20-GRRE | 20 (40 μL) | 200 μL |
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| KCNJ3BA-20-REGO | 20 (40 μL) | 200 μL |
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| KCNJ3BA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins and plays an important role in regulating heartbeat. It associates with three other G-protein-activated potassium channels to form a heteromultimeric pore-forming complex that also couples to neurotransmitter receptors in the brain and whereby channel activation can inhibit action potential firing by hyperpolarizing the plasma membrane. These multimeric G-protein-gated inwardly-rectifying potassium (GIRK) channels may play a role in the pathophysiology of epilepsy, addiction, Down's syndrome, ataxia, and Parkinson's disease. Alternative splicing results in multiple transcript variants encoding distinct proteins. [provided by RefSeq, May 2012]
Gene Details
Gene Symbol: KCNJ3
Gene Name: Potassium Voltage-gated Channel Subfamily J Member 3
Chromosome: CHR2: 155555092-155713014
Locus: 2q24.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: KCNJ3 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: KCNJ3-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping