KAZALD1 Break Apart FISH Probe
Empire Genomics’ KAZALD1 Break Apart FISH Probe is designed to flank the KAZALD1 gene and is typically used for detecting KAZALD1 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
SKU | Test Kits | Buffer | Dye Color | Order Now |
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KAZALD1BA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL | ||
KAZALD1BA-20-AQOR | 20 (40 μL) | 200 μL | ||
KAZALD1BA-20-GOGR | 20 (40 μL) | 200 μL | ||
KAZALD1BA-20-GORE | 20 (40 μL) | 200 μL | ||
KAZALD1BA-20-GRGO | 20 (40 μL) | 200 μL | ||
KAZALD1BA-20-GROR | 20 (40 μL) | 200 μL | ||
KAZALD1BA-20-GRRE | 20 (40 μL) | 200 μL | ||
KAZALD1BA-20-REGO | 20 (40 μL) | 200 μL | ||
KAZALD1BA-20-REGR | 20 (40 μL) | 200 μL |
Gene Summary
This gene encodes a secreted member of the insulin growth factor-binding protein (IGFBP) superfamily. The protein contains an insulin growth factor-binding domain in its N-terminal region, a Kazal-type serine protease inhibitor and follistatin-like domain in its central region, and an immunoglobulin-like domain in its C-terminal region. Studies of the mouse ortholog suggest that this protein may function in bone development and bone regeneration. This gene is hypomethylated and over-expressed in high-grade glioma compared to low-grade glioma, and thus the hypomethylated gene may be associated with cell proliferation and the shorter survival of patients with high-grade glioma. It is also one of numerous genes found to be deleted in a novel 5.54 Mb interstitial deletion, which is associated with multiple congenital anomalies. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]
Gene Details
Gene Symbol: KAZALD1
Gene Name: Kazal Type Serine Peptidase Inhibitor Domain 1
Chromosome: CHR10: 102820998-102825351
Locus: 10q24.31
FISH Probe Protocols
Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: KAZALD1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: KAZALD1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping