KAZALD1 FISH Probe
The KAZALD1 FISH probe is designed to hybridize to the KAZALD1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| KAZALD1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| KAZALD1-20-RE | 20 (40 μL) | 200 μL |  |
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| KAZALD1-20-GO | 20 (40 μL) | 200 μL |  |
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| KAZALD1-20-GR | 20 (40 μL) | 200 μL |  |
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| KAZALD1-20-AQ | 20 (40 μL) | 200 μL |  |
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| KAZALD1-20-DIG | 20 (40 μL) | 200 μL |  |
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| KAZALD1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a secreted member of the insulin growth factor-binding protein (IGFBP) superfamily. The protein contains an insulin growth factor-binding domain in its N-terminal region, a Kazal-type serine protease inhibitor and follistatin-like domain in its central region, and an immunoglobulin-like domain in its C-terminal region. Studies of the mouse ortholog suggest that this protein may function in bone development and bone regeneration. This gene is hypomethylated and over-expressed in high-grade glioma compared to low-grade glioma, and thus the hypomethylated gene may be associated with cell proliferation and the shorter survival of patients with high-grade glioma. It is also one of numerous genes found to be deleted in a novel 5.54 Mb interstitial deletion, which is associated with multiple congenital anomalies. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]
Gene Details
Gene Symbol: KAZALD1
Gene Name: Kazal Type Serine Peptidase Inhibitor Domain 1
Chromosome: CHR10: 102820998-102825351
Locus: 10q24.31
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: KAZALD1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: KAZALD1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping