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KANSL1 Break Apart FISH Probe

Empire Genomics’ KANSL1 Break Apart FISH Probe is designed to flank the KANSL1 gene and is typically used for detecting KANSL1 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in green and orange by default, but may be customized to meet your needs.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping
Download Datasheet Download FISH Protocol Download Material Safety Data Sheet

SKU Test Kits Buffer Dye Color Order Now
KANSL1BA-20-GROR  (Standard Design) 20 (40 μL) 200 μL
KANSL1BA-20-AQOR 20 (40 μL) 200 μL
KANSL1BA-20-GOGR 20 (40 μL) 200 μL
KANSL1BA-20-GORE 20 (40 μL) 200 μL
KANSL1BA-20-GRGO 20 (40 μL) 200 μL
KANSL1BA-20-GRRE 20 (40 μL) 200 μL
KANSL1BA-20-ORGR 20 (40 μL) 200 μL
KANSL1BA-20-REGO 20 (40 μL) 200 μL
KANSL1BA-20-REGR 20 (40 μL) 200 μL

Gene Summary

This gene encodes a nuclear protein that is a subunit of two protein complexes involved with histone acetylation, the MLL1 complex and the NSL1 complex. The corresponding protein in Drosophila interacts with K(lysine) acetyltransferase 8, which is also a subunit of both the MLL1 and NSL1 complexes. [provided by RefSeq, Jun 2012]

Gene Details

Gene Symbol: KANSL1

Gene Name: KAT8 Regulatory NSL Complex Subunit 1

Chromosome: CHR17: 46225373-46029915

Locus: 17q21.31

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Analysis in epithelial ovarian cancer identifies KANSL1 as a biomarker and target gene for immune response and HDAC inhibition

Epithelial ovarian cancer (EOC) is typically identified at advanced stage and usually incurable. This study analyzed 170 EOC tumors, searching for a possible link between patients’ gene profiles and survival. They were able to narrow in on KANSL1 as a master regulator of 3 key genes that monitor immune response. They found that KANSL1 alters expression of these genes through various DNA alterations, including KANSL1 amplifications, which were detected using our KANSL1 FISH probe.
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Product Details

Product: KANSL1 FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: KANSL1-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping