KANK1 Break Apart FISH Probe
Empire Genomics’ KANK1 Break Apart FISH Probe is designed to flank the KANK1 gene and is typically used for detecting KANK1 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
KANK1BA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL | ||
KANK1BA-20-AQOR | 20 (40 μL) | 200 μL | ||
KANK1BA-20-GOGR | 20 (40 μL) | 200 μL | ||
KANK1BA-20-GORE | 20 (40 μL) | 200 μL | ||
KANK1BA-20-GRGO | 20 (40 μL) | 200 μL | ||
KANK1BA-20-GROR | 20 (40 μL) | 200 μL | ||
KANK1BA-20-GRRE | 20 (40 μL) | 200 μL | ||
KANK1BA-20-REGO | 20 (40 μL) | 200 μL | ||
KANK1BA-20-REGR | 20 (40 μL) | 200 μL |
Gene Summary
The protein encoded by this gene belongs to the Kank family of proteins, which contain multiple ankyrin repeat domains. This family member functions in cytoskeleton formation by regulating actin polymerization. This gene is a candidate tumor suppressor for renal cell carcinoma. Mutations in this gene cause cerebral palsy spastic quadriplegic type 2, a central nervous system development disorder. A t(5;9) translocation results in fusion of the platelet-derived growth factor receptor beta gene (PDGFRB) on chromosome 5 with this gene in a myeloproliferative neoplasm featuring severe thrombocythemia. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome 20. [provided by RefSeq, Dec 2014]
Gene Details
Gene Symbol: KANK1
Gene Name: KN Motif And Ankyrin Repeat Domains 1
Chromosome: CHR9: 504702-746103
Locus: 9p24.3
FISH Probe Protocols
Protocol, Procedure, or Form Name | Last Modified | Download |
---|
Customer Publications
Product Details
Product: KANK1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: KANK1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping