JNKBP-1 FISH Probe
The JNKBP-1 FISH probe is designed to hybridize to the JNKBP-1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| MAPKBP1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| MAPKBP1-20-RE | 20 (40 μL) | 200 μL |  |
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| MAPKBP1-20-GO | 20 (40 μL) | 200 μL |  |
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| MAPKBP1-20-GR | 20 (40 μL) | 200 μL |  |
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| MAPKBP1-20-AQ | 20 (40 μL) | 200 μL |  |
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| MAPKBP1-20-DIG | 20 (40 μL) | 200 μL |  |
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| MAPKBP1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a scaffold protein that regulates the JNK (c-Jun N-terminal kinase) and NOD2 (nucleotide-binding oligomerization domain-containing protein 2) signaling pathways. The encoded protein interacts with another related JNK pathway scaffold protein, WDR62, via a conserved dimerization domain, and enhances JNK signaling. This protein may play a role in bacterial immunity by binding to the NOD2 receptor and negatively regulating downstream antibacterial and pro-inflammatory signaling. Mutations in this gene that impair cellular localization of the encoded protein cause a form of nephronophthisis, an autosomal-recessive kidney disorder, in human patients. [provided by RefSeq, May 2017]
Gene Details
Gene Symbol: MAPKBP1
Gene Name: Mitogen-activated Protein Kinase Binding Protein 1
Chromosome: CHR15: 42066631-42120053
Locus: 15q15.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: JNKBP-1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: MAPKBP1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping