JNK2-ALPHA1 FISH Probe
The JNK2-ALPHA1 FISH probe is designed to hybridize to the JNK2-ALPHA1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| MAPK9-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| MAPK9-20-RE | 20 (40 μL) | 200 μL |  |
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| MAPK9-20-GO | 20 (40 μL) | 200 μL |  |
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| MAPK9-20-GR | 20 (40 μL) | 200 μL |  |
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| MAPK9-20-AQ | 20 (40 μL) | 200 μL |  |
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| MAPK9-20-DIG | 20 (40 μL) | 200 μL |  |
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| MAPK9-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase targets specific transcription factors, and thus mediates immediate-early gene expression in response to various cell stimuli. It is most closely related to MAPK8, both of which are involved in UV radiation induced apoptosis, thought to be related to the cytochrome c-mediated cell death pathway. This gene and MAPK8 are also known as c-Jun N-terminal kinases. This kinase blocks the ubiquitination of tumor suppressor p53, and thus it increases the stability of p53 in nonstressed cells. Studies of this gene's mouse counterpart suggest a key role in T-cell differentiation. Several alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Sep 2008]
Gene Details
Gene Symbol: MAPK9
Gene Name: Mitogen-activated Protein Kinase 9
Chromosome: CHR5: 179660594-179719071
Locus: 5q35.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: JNK2-ALPHA1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: MAPK9-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping