JNK-46 FISH Probe
The JNK-46 FISH probe is designed to hybridize to the JNK-46 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| MAPK8-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
|
| MAPK8-20-RE | 20 (40 μL) | 200 μL |  |
|
| MAPK8-20-GO | 20 (40 μL) | 200 μL |  |
|
| MAPK8-20-GR | 20 (40 μL) | 200 μL |  |
|
| MAPK8-20-AQ | 20 (40 μL) | 200 μL |  |
|
| MAPK8-20-DIG | 20 (40 μL) | 200 μL |  |
|
| MAPK8-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation. Several alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Apr 2016]
Gene Details
Gene Symbol: MAPK8
Gene Name: Mitogen-activated Protein Kinase 8
Chromosome: CHR10: 49609686-49643183
Locus: 10q11.22
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|
Customer Publications
Product Details
Product: JNK-46 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: MAPK8-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping