JLNS1 FISH Probe
The JLNS1 FISH probe is designed to hybridize to the JLNS1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| KCNQ1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
|
| KCNQ1-20-RE | 20 (40 μL) | 200 μL |  |
|
| KCNQ1-20-GO | 20 (40 μL) | 200 μL |  |
|
| KCNQ1-20-GR | 20 (40 μL) | 200 μL |  |
|
| KCNQ1-20-AQ | 20 (40 μL) | 200 μL |  |
|
| KCNQ1-20-DIG | 20 (40 μL) | 200 μL |  |
|
| KCNQ1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a voltage-gated potassium channel required for repolarization phase of the cardiac action potential. This protein can form heteromultimers with two other potassium channel proteins, KCNE1 and KCNE3. Mutations in this gene are associated with hereditary long QT syndrome 1 (also known as Romano-Ward syndrome), Jervell and Lange-Nielsen syndrome, and familial atrial fibrillation. This gene exhibits tissue-specific imprinting, with preferential expression from the maternal allele in some tissues, and biallelic expression in others. This gene is located in a region of chromosome 11 amongst other imprinted genes that are associated with Beckwith-Wiedemann syndrome (BWS), and itself has been shown to be disrupted by chromosomal rearrangements in patients with BWS. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2011]
Gene Details
Gene Symbol: KCNQ1
Gene Name: Potassium Voltage-gated Channel Subfamily Q Member 1
Chromosome: CHR11: 2466220-2870340
Locus: 11p15.5-p15.4
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|
Customer Publications
Product Details
Product: JLNS1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: KCNQ1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping