JIP1 FISH Probe
The JIP1 FISH probe is designed to hybridize to the JIP1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| MAPK8IP1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| MAPK8IP1-20-RE | 20 (40 μL) | 200 μL |  |
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| MAPK8IP1-20-GO | 20 (40 μL) | 200 μL |  |
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| MAPK8IP1-20-GR | 20 (40 μL) | 200 μL |  |
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| MAPK8IP1-20-AQ | 20 (40 μL) | 200 μL |  |
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| MAPK8IP1-20-DIG | 20 (40 μL) | 200 μL |  |
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| MAPK8IP1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a regulator of the pancreatic beta-cell function. It is highly similar to JIP-1, a mouse protein known to be a regulator of c-Jun amino-terminal kinase (Mapk8). This protein has been shown to prevent MAPK8 mediated activation of transcription factors, and to decrease IL-1 beta and MAP kinase kinase 1 (MEKK1) induced apoptosis in pancreatic beta cells. This protein also functions as a DNA-binding transactivator of the glucose transporter GLUT2. RE1-silencing transcription factor (REST) is reported to repress the expression of this gene in insulin-secreting beta cells. This gene is found to be mutated in a type 2 diabetes family, and thus is thought to be a susceptibility gene for type 2 diabetes. [provided by RefSeq, May 2011]
Gene Details
Gene Symbol: MAPK8IP1
Gene Name: Mitogen-activated Protein Kinase 8 Interacting Protein 1
Chromosome: CHR11: 45907046-45928016
Locus: 11p11.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: JIP1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: MAPK8IP1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping