JBTS26 FISH Probe
The JBTS26 FISH probe is designed to hybridize to the JBTS26 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| KIAA0556-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| KIAA0556-20-RE | 20 (40 μL) | 200 μL |  |
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| KIAA0556-20-GO | 20 (40 μL) | 200 μL |  |
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| KIAA0556-20-GR | 20 (40 μL) | 200 μL |  |
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| KIAA0556-20-AQ | 20 (40 μL) | 200 μL |  |
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| KIAA0556-20-DIG | 20 (40 μL) | 200 μL |  |
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| KIAA0556-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a novel, evolutionarily conserved, ciliary protein. In human hTERT-RPE1 cells, the protein is found at the base of cilia, decorating the ciliary axoneme, and enriched at the ciliary tip. The protein binds to microtubules in vitro and regulates their stability when it is overexpressed. A null mutation in this gene has been associated with Joubert syndrome, a recessive disorder that is characterized by a distinctive mid-hindbrain and cerebellar malformation and is also often associated with wider ciliopathy symptoms. Consistently, in a serum-starvation ciliogenesis assay, human fibroblast cells derived from patients with the mutation display a reduced number of ciliated cells with abnormally long cilia. [provided by RefSeq, Feb 2016]
Gene Details
Gene Symbol: KIAA0556
Gene Name:
Chromosome: CHR16: 27561467-27791692
Locus: 16p12.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: JBTS26 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: KIAA0556-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping