JAM-3 FISH Probe
The JAM-3 FISH probe is designed to hybridize to the JAM-3 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| JAM3-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| JAM3-20-RE | 20 (40 μL) | 200 μL |  |
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| JAM3-20-GO | 20 (40 μL) | 200 μL |  |
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| JAM3-20-GR | 20 (40 μL) | 200 μL |  |
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| JAM3-20-AQ | 20 (40 μL) | 200 μL |  |
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| JAM3-20-DIG | 20 (40 μL) | 200 μL |  |
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| JAM3-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is localized in the tight junctions between high endothelial cells. Unlike other proteins in this family, the this protein is unable to adhere to leukocyte cell lines and only forms weak homotypic interactions. The encoded protein is a member of the junctional adhesion molecule protein family and acts as a receptor for another member of this family. A mutation in an intron of this gene is associated with hemorrhagic destruction of the brain, subependymal calcification, and congenital cataracts. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Apr 2011]
Gene Details
Gene Symbol: JAM3
Gene Name: Junctional Adhesion Molecule 3
Chromosome: CHR11: 133938819-134021652
Locus: 11q25
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: JAM-3 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: JAM3-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping