IYD FISH Probe
The IYD FISH probe is designed to hybridize to the IYD gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| IYD-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| IYD-20-RE | 20 (40 μL) | 200 μL |  |
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| IYD-20-GO | 20 (40 μL) | 200 μL |  |
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| IYD-20-GR | 20 (40 μL) | 200 μL |  |
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| IYD-20-AQ | 20 (40 μL) | 200 μL |  |
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| IYD-20-DIG | 20 (40 μL) | 200 μL |  |
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| IYD-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes an enzyme that catalyzes the oxidative NADPH-dependent deiodination of mono- and diiodotyrosine, which are the halogenated byproducts of thyroid hormone production. The N-terminus of the protein functions as a membrane anchor. Mutations in this gene cause congenital hypothyroidism due to dyshormonogenesis type 4, which is also referred to as deiodinase deficiency, or iodotyrosine dehalogenase deficiency, or thyroid hormonogenesis type 4. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009]
Gene Details
Gene Symbol: IYD
Gene Name: Iodotyrosine Deiodinase
Chromosome: CHR6: 150690027-150725765
Locus: 6q25.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: IYD FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: IYD-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping