ITGAL FISH Probe
The ITGAL FISH probe is designed to hybridize to the ITGAL gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ITGAL-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| ITGAL-20-RE | 20 (40 μL) | 200 μL |  |
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| ITGAL-20-GO | 20 (40 μL) | 200 μL |  |
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| ITGAL-20-GR | 20 (40 μL) | 200 μL |  |
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| ITGAL-20-AQ | 20 (40 μL) | 200 μL |  |
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| ITGAL-20-DIG | 20 (40 μL) | 200 μL |  |
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| ITGAL-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
ITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed on all leukocytes. LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: ITGAL
Gene Name: Integrin Subunit Alpha L
Chromosome: CHR16: 30483982-30534506
Locus: 16p11.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: ITGAL FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: ITGAL-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping