ITGA8 FISH Probe
The ITGA8 FISH probe is designed to hybridize to the ITGA8 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ITGA8-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
|
| ITGA8-20-RE | 20 (40 μL) | 200 μL |  |
|
| ITGA8-20-GO | 20 (40 μL) | 200 μL |  |
|
| ITGA8-20-GR | 20 (40 μL) | 200 μL |  |
|
| ITGA8-20-AQ | 20 (40 μL) | 200 μL |  |
|
| ITGA8-20-DIG | 20 (40 μL) | 200 μL |  |
|
| ITGA8-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
Integrins are heterodimeric transmembrane receptor proteins that mediate numerous cellular processes including cell adhesion, cytoskeletal rearrangement, and activation of cell signaling pathways. Integrins are composed of alpha and beta subunits. This gene encodes the alpha 8 subunit of the heterodimeric integrin alpha8beta1 protein. The encoded protein is a single-pass type 1 membrane protein that contains multiple FG-GAP repeats. This repeat is predicted to fold into a beta propeller structure. This gene regulates the recruitment of mesenchymal cells into epithelial structures, mediates cell-cell interactions, and regulates neurite outgrowth of sensory and motor neurons. The integrin alpha8beta1 protein thus plays an important role in wound-healing and organogenesis. Mutations in this gene have been associated with renal hypodysplasia/aplasia-1 (RHDA1) and with several animal models of chronic kidney disease. Alternate splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Apr 2014]
Gene Details
Gene Symbol: ITGA8
Gene Name: Integrin Subunit Alpha 8
Chromosome: CHR10: 15559087-15761770
Locus: 10p13
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|
Customer Publications
Product Details
Product: ITGA8 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: ITGA8-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping