ISOT FISH Probe
The ISOT FISH probe is designed to hybridize to the ISOT gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| USP5-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
|
| USP5-20-RE | 20 (40 μL) | 200 μL |  |
|
| USP5-20-GO | 20 (40 μL) | 200 μL |  |
|
| USP5-20-GR | 20 (40 μL) | 200 μL |  |
|
| USP5-20-AQ | 20 (40 μL) | 200 μL |  |
|
| USP5-20-DIG | 20 (40 μL) | 200 μL |  |
|
| USP5-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
Ubiquitin (see MIM 191339)-dependent proteolysis is a complex pathway of protein metabolism implicated in such diverse cellular functions as maintenance of chromatin structure, receptor function, and degradation of abnormal proteins. A late step of the process involves disassembly of the polyubiquitin chains on degraded proteins into ubiquitin monomers. USP5 disassembles branched polyubiquitin chains by a sequential exo mechanism, starting at the proximal end of the chain (Wilkinson et al., 1995 [PubMed 7578059]).[supplied by OMIM, Mar 2010]
Gene Details
Gene Symbol: USP5
Gene Name: Ubiquitin Specific Peptidase 5
Chromosome: CHR12: 6961284-6975795
Locus: 12p13.31
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|
Customer Publications
Product Details
Product: ISOT FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: USP5-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping