IRS-6 FISH Probe
The IRS-6 FISH probe is designed to hybridize to the IRS-6 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| DOK5-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| DOK5-20-RE | 20 (40 μL) | 200 μL |  |
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| DOK5-20-GO | 20 (40 μL) | 200 μL |  |
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| DOK5-20-GR | 20 (40 μL) | 200 μL |  |
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| DOK5-20-AQ | 20 (40 μL) | 200 μL |  |
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| DOK5-20-DIG | 20 (40 μL) | 200 μL |  |
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| DOK5-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is a member of the DOK family of membrane proteins, which are adapter proteins involved in signal transduction. The encoded protein interacts with phosphorylated receptor tyrosine kinases to mediate neurite outgrowth and activation of the MAP kinase pathway. Unlike other DOK family proteins, this protein does not interact with RASGAP. This protein is up-regulated in patients with systemic sclerosis and is associated with fibrosis induced by insulin-like growth factor binding protein 5. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jun 2014]
Gene Details
Gene Symbol: DOK5
Gene Name: Docking Protein 5
Chromosome: CHR20: 53092265-53267710
Locus: 20q13.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: IRS-6 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: DOK5-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping