IPO7 Break Apart FISH Probe
Empire Genomics’ IPO7 Break Apart FISH Probe is designed to flank the IPO7 gene and is typically used for detecting IPO7 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| IPO7BA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| IPO7BA-20-AQOR | 20 (40 μL) | 200 μL |
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| IPO7BA-20-GOGR | 20 (40 μL) | 200 μL |
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| IPO7BA-20-GORE | 20 (40 μL) | 200 μL |
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| IPO7BA-20-GRGO | 20 (40 μL) | 200 μL |
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| IPO7BA-20-GROR | 20 (40 μL) | 200 μL |
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| IPO7BA-20-GRRE | 20 (40 μL) | 200 μL |
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| IPO7BA-20-REGO | 20 (40 μL) | 200 μL |
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| IPO7BA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
The importin-alpha/beta complex and the GTPase Ran mediate nuclear import of proteins with a classical nuclear localization signal. The protein encoded by this gene is a member of a class of approximately 20 potential Ran targets that share a sequence motif related to the Ran-binding site of importin-beta. Similar to importin-beta, this protein prevents the activation of Ran's GTPase by RanGAP1 and inhibits nucleotide exchange on RanGTP, and also binds directly to nuclear pore complexes where it competes for binding sites with importin-beta and transportin. This protein has a Ran-dependent transport cycle and it can cross the nuclear envelope rapidly and in both directions. At least four importin beta-like transport receptors, namely importin beta itself, transportin, RanBP5 and RanBP7, directly bind and import ribosomal proteins. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: IPO7
Gene Name: Importin 7
Chromosome: CHR11: 9406168-9469674
Locus: 11p15.4
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: IPO7 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: IPO7-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping