IPO7 FISH Probe
The IPO7 FISH probe is designed to hybridize to the IPO7 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| IPO7-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| IPO7-20-RE | 20 (40 μL) | 200 μL |  |
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| IPO7-20-GO | 20 (40 μL) | 200 μL |  |
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| IPO7-20-GR | 20 (40 μL) | 200 μL |  |
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| IPO7-20-AQ | 20 (40 μL) | 200 μL |  |
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| IPO7-20-DIG | 20 (40 μL) | 200 μL |  |
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| IPO7-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The importin-alpha/beta complex and the GTPase Ran mediate nuclear import of proteins with a classical nuclear localization signal. The protein encoded by this gene is a member of a class of approximately 20 potential Ran targets that share a sequence motif related to the Ran-binding site of importin-beta. Similar to importin-beta, this protein prevents the activation of Ran's GTPase by RanGAP1 and inhibits nucleotide exchange on RanGTP, and also binds directly to nuclear pore complexes where it competes for binding sites with importin-beta and transportin. This protein has a Ran-dependent transport cycle and it can cross the nuclear envelope rapidly and in both directions. At least four importin beta-like transport receptors, namely importin beta itself, transportin, RanBP5 and RanBP7, directly bind and import ribosomal proteins. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: IPO7
Gene Name: Importin 7
Chromosome: CHR11: 9406168-9469674
Locus: 11p15.4
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: IPO7 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: IPO7-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping